Supports cognitive clarity and skin health
Centella asiatica, or Gotu Kola, is a leafy herb with a long history in traditional Asian wellness practices, often used for enhancing memory, mood, and skin health. It's commonly found in supplements for brain and skin, appealing to those seeking cognitive clarity or smoother skin.
About Gotu Kola
Historical Roots
Centella asiatica—commonly labeled Gotu Kola on supplement shelves—originates from ancient Asian wellness traditions. For centuries, its leaves have been brewed into teas or made into poultices. Modern formulas build on this heritage, combining it with recent scientific insights.
Nutritional Profile
The herb’s attention comes from its triterpenoids—naturally occurring compounds that might help neutralize cellular stress. These molecules attract scientific interest for their role in maintaining healthy tissue and cognitive functions under pressure. Research suggests potential support for collagen production, vascular health, and nerve function.
Traditional and Modern Uses
Historically, monks sipped it to clear the mind before meditation. Today, the biohacking community sometimes combines it with nootropics for a mental boost. On the dermatology side, Centella features in creams and capsules for skin suppleness and comfort.
Potential Applications
Centella also crosses into gut health blends, reflecting traditional uses, but its strongest associations remain with neurological benefits. It’s a contemporary tool for anyone interested in mind and body resilience.
Related Products
Formulated With
Learn about other ingredients that Gotu Kola is used alongside throughout the LVLUP range.
Detailed Information
Phytochemical Complexity
Centella asiatica contains a rich phytochemical profile dominated by pentacyclic triterpenoid saponins, such as asiaticoside and madecassoside, along with flavonoids, volatile oils, tannins, phytosterols, and amino acids. Triterpenoid saponins primarily stimulate fibroblast activity by promoting collagen synthesis via TGF-β signaling pathways and modulate MAPK signaling cascades relevant to neurogenesis and synaptic plasticity.
Neuroprotective Mechanisms
Preclinical studies indicate these constituents can cross the blood-brain barrier. In neurodegeneration models, Centella extracts influence oxidative stress response pathways, regulate inflammatory cytokine expression, and reduce beta-amyloid aggregation. Behavioral studies associate these molecular changes with improvements in learning and memory retention.
Dermal and Vascular Effects
For dermal applications, topical Centella stimulates VEGF-mediated angiogenesis and downregulates MMP-mediated extracellular matrix degradation—supporting wound healing and connective tissue resilience. Clinical trials of oral supplements have shown trends toward improved microcirculatory parameters and reduced anxiety scores.
Overall Impact
Centella asiatica provides wide-ranging cellular effects, including antioxidant and anti-inflammatory actions, alongside targeted mechanisms relevant to skin integrity, vascular maintenance, neuronal signaling, and stress adaptation. It’s commonly used as both a standalone botanical extract and within complexes aimed at nootropic or dermatological outcomes.
