About Grains of Paradise
Origins and Traditional Use
Grains of Paradise comes from a plant related to ginger. Its seeds resemble black pepper with a citrus twist, reminiscent of cardamom and mild chili. For generations, it has been a staple in West African recipes and remedies.
Role in Supplements
In modern supplements, Grains of Paradise is valued for its main bioactive compound, 6-paradol, which may activate brown adipose tissue (BAT). BAT is unique because it burns energy as heat instead of storing it like white fat.
Practical Applications
Supplements containing Grains of Paradise might support your body’s calorie-burning capabilities, even without intense exercise. It’s often found alongside botanicals like green tea or caffeine in metabolism-focused products.
Supplement Formulation
Companies standardize extracts to deliver consistent amounts of active compounds. It appears in capsules or powdered blends and is frequently combined with other metabolic health ingredients.
Related Products
Formulated With
Detailed Information
Bioactive Compounds
Aframomum melegueta seeds contain compounds like 6-paradol, 6-gingerol, and 6-shogaol. The focus is on 6-paradol, associated with BAT activation through TRPV1 channels on brown adipocytes, promoting thermogenesis via UCP1 expression.
Mechanism of Action
6-Paradol’s activation of TRPV1 can increase energy expenditure and reduce visceral fat. These actions don’t typically raise heart rate or blood pressure at standard dosages, distinguishing it from classic sympathomimetics.
Metabolic Benefits
Benefits include increased basal metabolic rate and improved glucose utilization through AMPK phosphorylation. These effects point to enhanced lipid oxidation and a favorable safety profile supported by traditional use and toxicological studies.